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If the GlobalProtect client has never been installed on the macOS system before, then follow these steps to fix this problem.

Initially you can just try removing and re-installing the GlobalProtect client. At some point during the installation you might be prompted to approve a third‐party extension (KEXT), PXPZ95SK77.

If that does not work you can manually approve the Palo Alto Networks third-party extension, PXPZ95SK77.

1. Boot the Apple system into macOS Recovery, https://support.apple.com/en-us/HT201314
2. Click the Utilities menu in the menu bar and select the Terminal application.
3. In the Terminal command prompt use the spctl kext-consent command below to add the Team ID PXPZ95SK77 to allow Palo Alto Networks as a third-party extension that macOS can load without user approval.
   spctl kext-consent add PXPZ95SK77
4. Restart the system
5. remove/uninstall the GlobalProtect client
6. re-install the GlobalProtect client